Structure of B. pumilus nitrilase

Structure of <em>B. pumilus</em> nitrilase

STUDENT: Andani Mulelu

The docking of a homology model of cyanide dihydratase (CynDpum) into a electron microscopy 3D reconstruction volume of CynDpum at pH 5.4. The location of the A, C and D surfaces are indicated in letters. A 90° rotation of the model shows the vacant densities proposed to be the location of the C-terminus.

The docking of a homology model of cyanide dihydratase (CynDpum) into a electron microscopy 3D reconstruction volume of CynDpum at pH 5.4. The location of the A, C and D surfaces are indicated in letters. A 90° rotation of the model shows the vacant densities proposed to be the location of the C-terminus.

The structure helps us visualise the CynDMpum at an atomic level and thus helps us understand the effects of certain stability conferring mutations on the overall structure of the enzyme.